Your brain runs on energy, the same as every other cell in your body. Good focus comes from giving it enough fuel, the raw materials to make its chemical messengers, and a nervous system that gets to fully reset at night.
The daytime supplements below cover the fuel and the raw materials. The nighttime ones help you wind down and recover, and the habits at the end help all of it work better.
- 16 oz filtered water with a pinch of sea salt and a squeeze of lemon
- 10 minutes outside in morning daylight, within 35 minutes of waking
- For extra benefit: light movement, like a short walk or lymphatic hops
- Energi+ 1 capsule
- TyroPhen 2 capsules, with or without food
- Create 4 to 6 capsules (3 to 4.5 g creatine)
- Energi+ 1 capsule
- Mag+ 4 capsules, 1 to 2 hours before bed
- Glycine 3 capsules, 30 to 60 minutes before bed
- Thea (L-theanine) 250 to 500 mg, 30 to 60 minutes before bed
- Encephalon 2 capsules with breakfast, or split across the day
- Purely K 1 capsule with a meal
- Panacea shilajit 3 tablets with breakfast
- Panax ginseng 1 to 2 g of root powder or 200 to 400 mg of extract every morning
- Adrenal Caps 2 capsules in the morning, 5 days a week
Add one new thing every 2 to 3 days, so you can feel what each one does.
Fuel and drive

Energi+
LifeBludA complete B vitamin complex in the forms your body uses directly. B vitamins are the spark plugs of energy production. Without enough of them, food doesn’t fully turn into usable energy, and focus is usually the first thing to fade. A 2016 review found B vitamins work as a team in the brain, which is why a full complex makes more sense than any single one.
How it works. B2 and B3 build FAD and NAD, the two carriers your mitochondria use to make ATP, your cells' energy currency. Benfotiamine, a well absorbed form of B1, helps turn glucose into fuel. B6 as P5P is needed to make dopamine, serotonin and GABA. Methylfolate and B12 drive methylation, which the brain uses to build and clear its chemical messengers. Splitting the dose keeps levels steady through the day. Take the second capsule by about 2 pm.
TyroPhen
LifeBludL-tyrosine and DL-phenylalanine, 225 mg of each per capsule. These are the raw materials your brain uses to make dopamine, the chemical of drive, motivation and "let’s get this done."
How it works. Phenylalanine becomes tyrosine, tyrosine becomes L-DOPA, and L-DOPA becomes dopamine and then norepinephrine. Both help run attention and alertness. A 2015 review of the human research found tyrosine helps protect working memory and mental flexibility when demands are high: stress, tiredness or juggling many tasks. Take it in the morning, with or without food.
Create
LifeBludMicronized creatine monohydrate. Most people know it for muscle. Your brain uses about a fifth of your body’s energy, and creatine supports that energy too.
How it works. Creatine stores phosphate as phosphocreatine, which rebuilds ATP within seconds when demand spikes. That buffer helps neurons keep firing during long stretches of thinking. A 2018 review of randomized trials found creatine improved short term memory and reasoning in healthy adults. You can take it any time of day, as long as you take it every day.
Calm, sleep and recovery
How well you focus tomorrow depends a lot on how well you sleep tonight. In a 2013 study in mice, the space between brain cells opened up by about 60% during sleep, which lets the brain flush out the waste it built up during the day.

Mag+
LifeBludMagnesium glycinate and magnesium taurate, two calm, well absorbed forms. About half of US adults get less magnesium than they need, and stress drains it faster. Low magnesium then makes the body more reactive to stress, which drains it even further.
How it works. Magnesium sits in the brain’s main "go" receptor and keeps it from over firing, while supporting GABA, the main "slow down" signal. It’s also needed for more than 300 enzymes, including every step that makes and uses ATP. Taurate adds taurine, which supports GABA and a steady heart rhythm. If your stools get loose, drop back a capsule.
Glycine
LifeBludA simple amino acid with a big effect on sleep quality. In human trials, 3 g before bed improved sleep quality and lowered next day fatigue, even after short nights.
How it works. Glycine acts on the brain’s internal clock and opens blood vessels in the hands and feet. That gently lowers your core temperature, which is the body’s natural signal for deep sleep. It’s also a calming messenger in the brainstem and spinal cord, and one of the building blocks of glutathione, your main antioxidant.
Thea (L-theanine)
LifeBludThe calming amino acid found in green tea. I take 500 mg at night, which is one capsule. Start at 250 mg if you’re new to it. In a 2019 trial, healthy adults who took 200 mg a day for four weeks slept better and reported less stress than on placebo.
How it works. L-theanine boosts GABA, the brain’s main "slow down" signal, and gently quiets the "go" signals. It also raises the alpha brain waves linked to calm, awake relaxation. That helps your mind settle without making you groggy, and it pairs well with magnesium and glycine.
The foundation layer
Add these once the core stack feels good. They support the brain, blood vessels and mitochondria over the long run.
Encephalon
MitolifeA brain formula built on three ingredients that work in different ways: BrainPhyt microalgae, phosphatidylserine and ginkgo.
How it works. BrainPhyt carries fucoxanthin, a marine antioxidant. In early lab research, it protected the fats in brain cells from oxidative damage. Phosphatidylserine is a core part of nerve cell membranes and supports memory and recall. In a 2014 trial in children with ADHD, 2 months of phosphatidylserine improved attention and short term memory. Ginkgo supports blood flow to the brain. It isn’t stimulating, so it won’t make you wired.
Purely K
MitolifeVitamin K1 plus K2 in both the MK-4 and MK-7 forms. Most modern diets are low in K2 because we eat far less aged cheese, liver and pasture raised yolks.
How it works. K2 switches on proteins that move calcium into bones and teeth and keep it out of arteries and soft tissue. In a large Dutch study of 4,800 adults, people who ate the most K2 had about half the rate of severe artery calcification, and 57% lower risk of dying from heart disease, compared with those who ate the least. Healthy vessels mean steady blood flow, and the brain depends on that flow for oxygen and fuel. It’s fat soluble, so take it with food.
Panacea shilajit
MitolifePure shilajit resin from the Altai mountains in tablet form. A rich natural source of fulvic acid and dozens of trace minerals.
How it works. Fulvic acid helps carry minerals into cells, and early animal research suggests shilajit supports energy production in the mitochondria. In a 2019 trial, 8 weeks of 500 mg a day helped people hold onto their strength during fatiguing exercise. Quality matters with shilajit, so buy from a source you trust.
These are great on days when you need extra focus or energy.
Panax ginseng
Any trusted brandAsian ginseng root, one of the most studied herbs for energy and mental stamina. I take it every morning because it’s gently energizing. If you use an extract, choose a standardized one that lists the amount of ginsenosides on the label. The extract used in most studies has about 4%.
How it works. Ginseng’s active compounds, called ginsenosides, help the body handle stress and use glucose for fuel. In a 2005 trial, a single dose improved mental math and lowered mental fatigue during long stretches of hard thinking. A 2018 review of 10 studies found ginseng a promising option for fatigue, with a low risk of side effects.
Adrenal Caps
SolarayA freeze dried adrenal concentrate with eleuthero, licorice root, gotu kola and clove. I take it in the morning to extend my daytime cortisol, the hormone that gets you up and keeps you going.
How it works. Licorice root slows the enzyme that breaks cortisol down, so the cortisol you make in the morning lasts longer. Eleuthero is a classic adaptogen used to support stamina under stress. Take it early so evening cortisol can fall and sleep comes easily. Cortisol raises blood sugar, so make sure your blood sugar isn’t running high before you add this one.
Habits that make focus easier
These habits help your brain make the most of everything above. Start with one or two.
Hydrate, get sun, move
Start with 16 oz of filtered water, a pinch of sea salt and a squeeze of lemon. You wake up after hours without water, and even mild dehydration dulls focus. In a 2011 study, losing about 1.5% of body water weakened attention and working memory and raised fatigue.
Then spend 10 minutes outside in morning daylight within 35 minutes of waking, without sunglasses. Do 20 minutes if it’s cloudy. Morning light sets your body clock. In a 2013 study, one week of natural light shifted people’s internal clocks to line up with sunrise and sunset.
For extra benefit, move while you’re out there. Take a short walk, or do lymphatic hops: small, gentle bounces on the balls of your feet for 1 to 2 minutes.
Work in blocks, then truly rest
Plan focused blocks of 60 to 90 minutes, then step away for 10 to 15 minutes. A 2022 review of 22 studies found short breaks raised energy and lowered fatigue. Two strong blocks a day is a great day of deep work.
Put your phone in another room
In a 2017 study of about 800 people, those whose phones were in another room scored best on memory and problem solving tests. A phone on the desk lowered scores, even face down and silent.
Write the next tiny step
Before you stop, write the very next action and when you’ll do it. "At 9 am, open the draft and edit the first paragraph." A 2006 review of 94 studies found that planning when and where you’ll act made people much more likely to follow through.
Sit for 13 minutes a day
Close your eyes and follow your breath and the feeling of your body. When your mind wanders, bring it back. In a 2019 trial, new meditators who did 13 minutes a day for 8 weeks improved attention, memory and mood.
Move between blocks
Take a brisk 10 minute walk between blocks. A 2012 review of 79 studies found a single bout of exercise gives thinking a small lift during and after. Fidgeting while you work is fine too. In a 2015 study, kids with ADHD did better on memory tasks while they moved more.
Eat protein at breakfast
Aim for about 30 g. Eggs, meat, Greek yogurt or a clean protein shake. Protein supplies the same building blocks TyroPhen does, and it slows how fast sugar hits your blood, so energy stays steadier through the morning.
Protect your evenings
Dim the lights after sunset. In a 2011 study, ordinary room light before bed cut melatonin time by about 90 minutes. Keep caffeine before noon. Caffeine taken even 6 hours before bed cut sleep by more than an hour in a 2013 trial. Wake at the same time every day, weekends included.
Check your labs
If you're tired no matter what you do, ask for ferritin (your iron stores), B12 and vitamin D on your next blood test. Low iron can drain your energy even when you're not anemic. In a 2012 trial of 198 women with low ferritin but normal blood counts, 12 weeks of iron cut fatigue by about 48%, compared with 29% on a placebo. The Vitality Code lists the lab markers I'd look at first.
Reset with NSDR before 3 pm
NSDR (non sleep deep rest), also called yoga nidra, is a guided practice where you lie down and stay awake while your body fully relaxes. Do 15 to 25 minutes before 3 pm, after a long stretch of focus. Free guided recordings are easy to find on YouTube. In a small 2002 brain scan study, yoga nidra raised dopamine release by about 65%.
End your shower cold
Finish with 30 seconds to 2 minutes of cold water in the morning. In a 2008 study, a short dip in very cold water raised norepinephrine 2 to 3 times. Norepinephrine is one of the brain's main alertness signals. If you have a heart condition, check with your doctor first.
Breathe with long exhales
Breathe in through your nose, take one more short sip of air on top, then let it all out slowly through your mouth. Do this for 5 minutes. In a 2023 Stanford trial, 5 minutes a day of this improved mood and calmed the body more than the same time spent meditating.
If you use caffeine, pair it
Consider pairing it with 100 to 200 mg of L-theanine, a calming amino acid found in green tea. Also have some fuel in your system before or with your caffeine, even if it's just some light carbs like fruit. In a 2008 trial, adding 100 mg of L-theanine to caffeine improved accuracy when people switched between tasks and made them less easily distracted.
Use the code COACH at checkout for everything from LifeBlud and Mitolife. It gets you a good price and supports my work.
More from me
This guide covers four of the eight pillars I measure in the Vitality Code: Morning Sunlight & Nature, Sleep Hygiene, Mitochondrial Function, and Nervous System & Gut.
The research
- Kennedy 2016. B Vitamins and the Brain: Mechanisms, Dose and Efficacy: A Review. Nutrients.
- Jongkees et al. 2015. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands: A review. J Psychiatr Res.
- Avgerinos et al. 2018. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Exp Gerontol.
- Xie et al. 2013. Sleep drives metabolite clearance from the adult brain. Science.
- Rosanoff et al. 2012. Suboptimal magnesium status in the United States: are the health consequences underestimated? Nutr Rev.
- Pickering et al. 2020. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients.
- Bannai et al. 2012. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Front Neurol.
- Kawai et al. 2015. The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology.
- Hirayama et al. 2014. The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial. J Hum Nutr Diet.
- Geleijnse et al. 2004. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J Nutr.
- Keller et al. 2019. The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels. J Int Soc Sports Nutr.
- Ganio et al. 2011. Mild dehydration impairs cognitive performance and mood of men. Br J Nutr.
- Reay et al. 2005. Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. J Psychopharmacol.
- Arring et al. 2018. Ginseng as a treatment for fatigue: a systematic review. J Altern Complement Med.
- Stewart et al. 1987. Mineralocorticoid activity of liquorice: 11 beta hydroxysteroid dehydrogenase deficiency comes of age. Lancet.
- Wright et al. 2013. Entrainment of the human circadian clock to the natural light-dark cycle. Curr Biol.
- Albulescu et al. 2022. "Give me a break!" A systematic review and meta-analysis on the efficacy of micro-breaks for increasing well-being and performance. PLoS One.
- Ward et al. 2017. Brain drain: the mere presence of one’s own smartphone reduces available cognitive capacity. J Assoc Consum Res.
- Gollwitzer and Sheeran 2006. Implementation intentions and goal achievement: a meta-analysis of effects and processes. Adv Exp Soc Psychol.
- Basso et al. 2019. Brief, daily meditation enhances attention, memory, mood, and emotional regulation in non-experienced meditators. Behav Brain Res.
- Chang et al. 2012. The effects of acute exercise on cognitive performance: a meta-analysis. Brain Res.
- Sarver et al. 2015. Hyperactivity in Attention-Deficit/Hyperactivity Disorder (ADHD): Impairing Deficit or Compensatory Behavior? J Abnorm Child Psychol.
- Gooley et al. 2011. Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. J Clin Endocrinol Metab.
- Drake et al. 2013. Caffeine effects on sleep taken 0, 3, or 6 hours before going to bed. J Clin Sleep Med.
- Vaucher et al. 2012. Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial. CMAJ.
- Leppäluoto et al. 2008. Effects of long-term whole-body cold exposures on plasma concentrations of ACTH, beta-endorphin, cortisol, catecholamines and cytokines in healthy females. Scand J Clin Lab Invest.
- Balban et al. 2023. Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Rep Med.
- Kjaer et al. 2002. Increased dopamine tone during meditation-induced change of consciousness. Brain Res Cogn Brain Res.
- Owen et al. 2008. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci.
- Hidese et al. 2019. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients.